Over the years, Pam has either learned how to wear a permanent pucker or she's had lip augmentation.
One of the most common materials used in lip jobs is collagen, derived from the carcasses of animals, typically cows. Another is Hylaform, which comes from bird carcasses.
There are now alternatives that are not derived from animals, such as Restylane and Achyal, but even these were tested on animals before going to market.